frequently asked questions

 

What is CBD?

The cannabis plant contains more than 100 different naturally-occurring chemical compounds known as phytocannabinoids (or just “cannabinoids,” as most people casually refer to them), which interact with the body's endocannabinoid system in ways that scientists and researchers alike are still working to understand.

One of those cannabinoids is CBD, or cannabidiol (pronounced cann-a-bid-EYE-ol). CBD is non-intoxicating and non-psychoactive, which means it doesn’t get you “high” — and there's a growing body of evidence that it has a number of health benefits.

 

What is the Endocannabinoid System?

The Endocannabinoid System is a biological network found within the body made up of Cannabinoid receptors found on the surface of cells, Endocannabinoids (which are small molecules that activate the cannabinoid receptors), and metabolic enzymes that break down the endocannabinoids after they are used. What this equates to is a system within your body that plays a crucial role in regulating physiology, mood, modulation of pain and inflammation, and everyday experience.

It is now established scientific fact that cannabinoids and other components of cannabis can affect or modulate many physiological systems in the human brain and body. While the two cannabinoids that have been studied most extensively are THC and CBD, there are a multitude of other cannabinoids we are only just now beginning to learn about or even become aware of. Many of these cannabinoids actually occur naturally in the human brain and body, hinting at a much deeper evolutionary relationship between the human body and the cannabis plant than recent history might suggest.

What is the difference between Hemp and Marijuana?

The first thing you should be aware of is that yes, marijuana and hemp are both varieties of Cannabis (cannabis sativa, to be precise). But that doesn’t mean they are the same thing. In fact, they are quite different, both in appearance and in effect.

The key ingredient that sets these two apart is THC, which stands for Tetrahydrocannabinol. THC is another naturally-occuring cannabinoid that appears in the plant, and is famous for being the active ingredient that gets you “high.”  While Marijuana can contain THC in potencies as high as 35%, Hemp by its legal definition contains less than 0.3% THC. This means there is not enough THC content to produce psychoactive effects, yielding a “high.”

To clarify:

  • Marijuana is most often associated with THC and has greater than 0.3% THC (the only phytocannabinoid that gets you "high").

  • Hemp extract is often associated with CBD, a health & wellness phytocannabinoid, and has less than 0.3% THC. Hemp CBD can be considered “not psychoactive.”

What is “Full Spectrum” Hemp Extract and how is it different from hemp seed oil or CBD isolate?

Full Spectrum Hemp Extract, also known as Whole Plant Extract, refers to the end result of a process by which pure oil is extracted from the Hemp plant containing the “full spectrum” of cannabinoids and compounds that were present in the original plant while it was still in the ground.

Unlike isolated or synthetic cannabinoids, full-spectrum hemp extract or oil contains a wide variety of cannabinoids, as well as many essential vitamins and minerals, fiber, proteins, fatty acids, chlorophyll, flavonoids, and terpenes. This key distinction makes a big difference in how the body responds to the hemp itself, and the compounded health benefits that come with it.

Put more simply: Full Spectrum Hemp Extract goes much further in benefiting the body than isolate-based CBD products (isolated CBD in powder form, mixed into other dilution agents). When you have all the compounds of the plant working in cooperation together, a more powerful result is achieved, often referred to as “the Entourage Effect” (see below for more info). Be sure to always look for Full Spectrum Extract in your CBD products!

Entourage Effect?

The Entourage Effect is a phenomenon which occurs when hundreds of naturally-occurring components within the cannabis or hemp plant interact together with the human body to produce a stronger effect than any single, isolated component alone. The combined cannabinoids not only are healthier when consumed together, they actually amplify each other’s effects to create something even stronger, which in turn yields a more impactful treatment for a variety of undesired medical symptoms. Our sister organization, CW Hemp, actually has a great video with a short visual explanation of this:  https://vimeo.com/275524880

Sources:
*Gupta, S. (2014). Medical marijuana and ‘the entourage effect.' Retrieved from http://www.cnn.com/2014/03/11/health/gupta-marijuana-entourage/

**Rasoanaivo, P., Wright C.W., Willcox, M.L., and Gilbert, B. (2011). Whole plant extracts versus single compounds for the treatment of malaria: synergy and positive interactions. Retrieved from http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3059462/.

Why Vape over other delivery methods?

It’s all a matter of preference, really. A vast majority of the options for consuming Hemp CBD involve oils and sublingual tinctures, which have become the standard. It also should be stated that everyone’s body reacts to treatment methods in different ways. What works well for one person may not work as well for another. Always keep that in mind. But there are a few reasons why you might prefer a vape pen.

The main reason is Bioavailability. In short, Bioavailability is the degree and rate at which a substance is absorbed into the bloodstream. There are a few primary ways to consume CBD. Let’s look at some and why Bioavailability is important:

1. Oral CBD consumption is a fairly common method. Basically this would involve any food or beverage product containing CBD. The oral bioavailability of CBD can be anywhere from 10-19%.* That’s obviously pretty low, and this is mainly due to the liver doing its job during “First-Pass” digestion, where much of what is consumed is broken down into unusable parts and disposed of. Any remaining CBD gets stored in fat cells where it can wait for days to be deployed by the body. This is why it is good to consume high-potency CBD edibles, because you can lose as much as 80% just by digesting!

2.  Sublingual CBD application is another common method. This is where a CBD oil is absorbed through a large vein under the tongue called the Sublingual Gland. The Bioavailability of this method is usually between 19-35%,* again highlighting the wisdom of leaning toward higher potency sublingual tinctures, as much is lost in the process.

3. CBD Vapor, or “CBD vaping,” is another way. The bioavailability via inhalation can reach as high as 56%,* making it far and away the body’s most effective method of administration. The reason for this is the lungs, and their ability to avoid the “First-Pass” effect by connecting the CBD directly to blood vessels and the blood-brain barrier. Think of vaping as a shortcut to the bloodstream for the CBD.

4. CBD Lotions, balms, and salves are all also common methods, however their bioavailability is extremely low due to the human skin’s natural responsibility to protect from outside influence. Basically the positive effects of these products are limited to localized relief in a specific area of application in liberal amounts.


There’s also 1 other reason why a CBD vape pen might be your preferred method, and that is speed of absorption rate. It is common to feel effects of a vaporized substance within 60 seconds, while orally ingested items typically have to make it through digestion, which can take an hour. So if you are looking for quick relief, there’s no contest. A vape pen will always get your CBD into the system fastest.

Sources:
*Mechoulam R, Parker LA, Gallily R (November 2002). "Cannabidiol: an overview of some pharmacological aspects". Journal of Clinical Pharmacology. 42 (11 Suppl): 11S–19S. doi:10.1002/j.1552-4604.2002.tb05998.x. PMID 12412831.

*https://www.ncbi.nlm.nih.gov/pubmed/22716155

*https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2689518/

Why use PG and VG as additives?

The thing you’re really probably wondering is “why add anything at all?”  And the answer has to do with the fact that, because we use a Full Spectrum Hemp Extract in our oil, we have to dilute it a little in order to adhere to the federal law requiring a less than 0.3% THC level of the total solution.

But isn’t PG bad?

There has been a lot of controversy surrounding Propylene Glycol, commonly known as “PG,” in recent years. But much of the information floating around on the internet is misguided or taken out of context. Let’s clear up some of that confusion.

PG is currently used in asthma inhalers and nebulizers used by lung transplant patients, and has been for decades. It is licensed for inhalable and injectable medicines by all authorities, and licensed for long-term high-volume inhalation under all employee health regulations. Clinical research has proven PG is safe for inhalation in absolute terms: it has 70 years of documented history for this purpose without any major incidents or long term damage. With that being acknowledged, however, these use cases had never involved heating of the liquid, which is something necessary during vaporization of CBD.

In a study conducted by the New England Journal of Medicine article regarding PG and formaldehyde,* (The study which originally caused the protests against using PG) it was discovered that at 5 volts of 4-second puffs (a high voltage for vaping and a longer puff than necessary), solutions containing Glycerol substances began to convert to harmful substances like formaldehyde. Basically it was being unnecessarily overcooked.
What people don’t talk about is that within that same study, it was shown that when PG was vaped at sub-4 volt levels, no formaldehyde was produced or detected at all.

It is this reason that we use the specific battery that we do. Stanley Brothers Vape batteries have a maximum output of 3.7 volts and are physically incapable of reaching the dangerous level of 5 volts. Additionally, we test all ingredients in our solution to ensure it is completely free of pesticides, herbicides, fungicides, residual solvents, heavy metals, aflatoxins, and other potentially harmful additives like polyethylene glycol, diacetyl, acetoin, or acetyl propionyl.


In the wake of this confusing controversy, a variety of new dilution and flavor oils have begun to be used in vapor solutions. Unfortunately none of these have undergone the rigorous testing that PG has undergone, and therefore are scientifically unproven to be considered “safe.” This is why we made the decision to stay with PG. Because more is known about PG as a vaporizable substance than any of the other options combined, and there are clear, safe parameters for responsible usage which we adhere to.

At Stanley Brothers Vape, we are committed to safety, health, and science. We will always follow the scientific community over rumors and over-reactive industry trends. We will always invest in safe, innovative ways for you to administer cannabinoids to the body in the most effective way possible.

Sources:
*https://www.nejm.org/doi/full/10.1056/NEJMc1413069?mc_cid=a4063cd4fe&mc_eid=ca288e7635

What is proper dosage?

Regardless of what anyone tells you, there is still no standard dosage or treatment when it comes to cannabinoids. In fact, the one thing that is widely accepted is that everyone is affected differently when consuming cannabinoids due to their own individual endocannabinoid systems. For this reason, we recommend going slow. We should specify that this is not medical advice and we are not licensed medical practitioners, but we consider it wise to take one’s time and ease into your usage.

Our recommendation is to take short, measured puffs on the vape pen of 1-2 seconds in length, releasing your lips from the vape pen and continuing to inhale oxygen as a normal breath. Then exhale like you would normally. It is not necessary to hold your breath and the CBD vapor in your lungs, in fact studies suggest this has no increase in efficacy whatsoever.*
Wait about 60 seconds to notice effect, then repeat again as needed.

*Source:  https://www.ncbi.nlm.nih.gov/pubmed/2554344

How do I use the vape pen?

STEP 1:  Open box.

STEP 2:  Inhale through the end with the small opening in the center. The opposing end with the SB logo will light up during inhalation. Take short, measured puffs on the vape pen of 1-2 seconds in length, releasing your lips from the vape pen and continuing to inhale oxygen as a normal breath. Then exhale like you would normally. It is not necessary to hold your breath and the CBD vapor in your lungs, in fact studies suggest this offers no increase in efficacy.
Wait about 60 seconds to notice effect, then repeat again as needed.

STEP 3:  Repeat as needed.

What is the life of the pen?

There is no accurate way to calculate exactly how long your CBD vape pen will last due to the number of random variables. For that reason, we’ve provided you the window into the chamber containing your CBD solution. When there’s nothing left, and/or your puffs are starting to come up dry… you’re empty!  Time to buy a new one!

How do I check the Certificate of analysis?

On every box is a QR code. If you scan the code with a QR scanner (you can download QR scanner apps for free on any app store), you will be taken directly to the lab testing results for that specific vape pen and batch. Our independent lab tests all include Potency, Pesticide, and Residual Solvents results. We want to make sure every consumer is given transparency into our products while understanding we take our 100mg CBD/pen statement seriously.

All ingredients in our solution are independently tested to ensure they are completely free of pesticides, herbicides, fungicides, residual solvents, heavy metals, aflatoxins, and other potentially harmful additives like polyethylene glycol, diacetyl, acetoin, or acetyl propionyl. Go ahead and check the results for yourself!

Is there THC in our vape pens? Can it affect a drug test?

There are indeed trace amounts of THC in our vape pens, but not enough to get you “high.” In accordance with Federal Law regarding Industrial Hemp sourced CBD, there is a small amount of THC which is allowed to be present in the solution, as long as it is less than 0.3% total THC. Stanley Brothers Vape pens are compliant with that law.

If you are worried about failing a drug test due to the THC content, we cannot advise that you use our vape pen, as there is a slight chance that the THC could indeed influence the outcome of the drug test. Even if the the THC content is less than 0.3%, it is still possible to “pop” on the test, therefore it simply isn’t worth the risk.